# Installation ## Requirements The Census API requires a Linux or MacOS system with: - Python 3.8 to Python 3.11. Or R, supported versions TBD. - Recommended: >16 GB of memory. - Recommended: >5 Mbps internet connection. - Recommended: for increased performance use the API through a AWS-EC2 instance from the region `us-west-2`. The Census data builds are hosted in a AWS-S3 bucket in that region. ## Python (Optional) In your working directory, make and activate a virtual environment or conda environment. For example: ```shell python -m venv ./venv source ./venv/bin/activate ``` Install the `cellxgene-census` package via pip: ```shell pip install -U cellxgene-census ``` There are also "experimental" add-on modules that are less stable than the main API, and may have more complex dependencies. To install these, ```shell pip install -U cellxgene-census[experimental] ``` If installing in a Databricks notebook environment, use `%pip install`. Do not use `%sh pip install`. See the [FAQ](cellxgene_census_docsite_FAQ.md#why-do-i-get-an-error-when-running-import-cellxgene-census-on-databricks). ## R If installing from **Ubuntu**, you may need to install the following libraries via `apt install`, `libxml2-dev` `libssl-dev` `libcurl4-openssl-dev`. In addition you must have `cmake` v3.21 or greater. If installing from **MacOS**, you will need to install the [developer tools `Xcode`](https://apps.apple.com/us/app/xcode/id497799835?mt=12). **Windows** is not supported. From an R session, first install `tiledb` from R-Universe, the latest release in CRAN is not yet available. ```r install.packages( "cellxgene.census", repos=c('https://chanzuckerberg.r-universe.dev', 'https://cloud.r-project.org') ) ``` To be able to export Census data to `Seurat` or `SingleCellExperiment` you also need to install their respective packages. ```r # Seurat install.packages("Seurat") # SingleCellExperiment if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("SingleCellExperiment") ```